Senator Sam Nunn and philanthropist Ted Turner and describes itself as a "a nonprofit, nonpartisan global security organization focused on reducing nuclear, biological, and emerging technology threats imperiling humanity.

[6] NTI advisor Warren Buffett provided $50 million to jump-start the reserve, which is owned and managed by the International Atomic Energy Agency and located in Kazakhstan.

[7] In 2002, NTI provided much of the financial support for a joint US-Russian mission to remove 100 pounds of highly enriched uranium from the Vinča Nuclear Institute in Serbia, to be flown to Russia.

[16] In 2003, NTI created the Middle East Consortium for Infectious Disease Surveillance (MECIDS) with participation from Israel, Jordan, and the Palestinian Authority.

[20] NTI also produced the 2010 documentary film Nuclear Tipping Point, which was screened by President Obama at the White House in April 2010[21] and featured on The Colbert Report.

[23] Co-chaired by Moniz, Nunn, and Ted Turner, NTI is governed by a board of directors with both current and emeritus members from around the globe.