Nyctitheriidae is a family of extinct eulipotyphlan insectivores known from the Paleocene and Eocene epochs of North America and Asia and persisting into the Oligocene of Europe.

Several genera, including Nyctitherium, Paradoxonycteris, and Wyonycteris, have initially been described as bats, although the family is more frequently placed in the order Eulipotyphla.

[4] Many additional species of Nyctitheriidae from Asia, Europe, and North America have been recognized in the subsequent decades.

[5][6] A recent phylogenetic analysis placed Nyctitheriidae within Eulipotyphla,[5] although Hooker (2001, 2014) has argued based on similarities in the limb bones for a relationship with Euarchonta, instead.

[8] Beard and Dawson (2009) considered Placentidentinae, previously thought to be related to Dermoptera, to also represent a subfamily within Nyctitheriidae.