Orville Frank Tuttle (June 25, 1916, Olean, New York – December 13, 1983, Tucson, Arizona) was an American mineralogist, geochemist, and petrologist, known for his research on granites and feldspars, with pioneering development of apparatus in experimental petrography.
He then matriculated at Massachusetts Institute of Technology for his doctoral work, which was interrupted by the Second World War, in which he was engaged in wartime research on crystal growth and characterization.
In 1947, he started his collaboration in experimental petrography with Norman L. Bowen at the Geophysical Laboratory of the Carnegie Institution in Washington.
In 1965, he moved to Stanford University, where he was granted sick leave in 1967 and formally resigned in 1971.
In 1977 he received a tentative diagnosis of Alzheimer's disease and moved to a nursing home.