Oak Knoll is an unincorporated area in Manatee County, Florida, in the United States.

Oak Knoll was a small unincorporated community located near and named after the 100-acre Oak Knoll Grapefruit and Orange Company's farm (also known as Huyler's Grove).

Located southeast of Parrish and just north of Bethany, Oak Knoll was an agricultural community built around the citrus industry.

Although planned subdivision was never built, a community of farmers and winter residents developed.

[2] By the fall of 1914, a large hotel was built by the Manatee River Developing Company in the center of the tract.