In 2012, Oh defied his parents' wishes for him to study in the States and moved to Seoul with no financial support to pursue music.
Oh originally created Hyukoh as a one-man band, but formed the current four-piece in 2014 under the same name with bassist Im Dong-geon, guitarist Lim Hyun-jae and drummer Lee In-woo.
Oh has collaborated with a variety of South Korean artists across multiple genres, including hip hop group Epik High, singer-songwriter IU, rapper-producer Code Kunst and indie singer Car, the garden.
In January 2018, Oh ventured into the house and techno genre through a collaboration with indie artist Cifika, entitled "Momom" (몸마음).
In 2015, Oh released a cover of Lee Moon-se's "A Little Girl" (소녀) for the soundtrack of the South Korean drama series Reply 1988.