Through the entirety of its route, SR 373 also passes through Wayne National Forest.

[2] The route begins at the intersection of SR 93 and Puckett Cemetery Road in Lawrence County's Elizabeth Township.

Traveling through the Wayne National Forest, the bulk of the state highway's surrounding landscape is primarily wooded.

As the highway bends to the east, a vastness of trees appear roadside, on both sides of the route.

Turning to the north, SR 373 passes the Dean State Fire Road intersection, then, upon entering Decatur Township, also enters the Dean State Forest proper.