Its eastern terminus is at a signalized intersection with SR 51 about 0.5 miles (0.80 km) southeast of Millbury.

SR 795, which was created in the late 1930s, serves a number of small towns in northern Wood County.

In 2005 and 2006, SR 795 was one of the main detour routes for I-280 during the construction of the Maumee River Crossing.

The segment of SR 795 that runs between I-75 and I-280 is included within the National Highway System, a system of highways that are determined to be the most important for the economy, mobility and defense of the country.

[6][7] This upgrade included the construction of viaducts over a pair of parallel railyards, as well as a parclo interchange at East Broadway Street (which previously conveyed the route between Indiana Avenue and Moline-Martin Road) in Moline.