ODOL is responsible for supervising the administration of all state laws relating to labor and workplace safety and gathers and publishes information about the workforce of Oklahoma.

The present Commissioner of Labor is Leslie Osborn who was elected by the people in November 2018 and took office January 2019.

In August 1907 delegates from the Twin-Territorial Federation of Labor, the State Farmers' Union, and the Railroad Brotherhoods met in Shawnee and formulated a list of 24 demands for the forthcoming constitutional convention.

Since its inception, the Oklahoma Department of Labor has functioned continuously for more than 100 years under the direction of 18 different Commissioners and 22 governors.

The present Commissioner of Labor is Lesie Orborn who was elected by the people in November 2018 and took office January 2019.