[3] The site is protected by the Yukon Wildlife Ordinance and Migratory Birds Convention Act.

The habitat is an important breeding area for aquatic mammals and peregrine falcons, is used for summer moulting by waterfowl, and is an autumn staging site for various species of birds.

[4] The Bluefish Caves, another important area with early human presence, are located about 75 km southwest of the Old Crow Flats.

[10] Many animals are represented in fossils uncovered in Old Crow Flats, including mammoths, mastodons, giant beavers, ground sloths, camels, horses, giant bison, short-faced bears, American lions, and short-faced skunks, among others.

Mammoth bones radiocarbon dated between 25,000 and 40,000 years old display signs of human tool production and butchery.