On October 20, 2019, the Cabinet of Ministers of Ukraine approved Oleksiy Chernyshov's candidacy for the position of the Head of the Kyiv Regional State Administration.

Its priorities included decentralization, infrastructure development in Kyiv Oblast, improving rail connectivity, constructing schools, kindergartens, and stadiums, and enhancing the region's investment attractiveness.

[9] Chernyshov also helped to oversee the Great Construction, a controversial project announced by President Volodymyr Zelenskyy in 2020 to modernize infrastructure in the country.

[10] On 6 October 2020, Chenyshov and European Investment Bank Vice President Teresa Czerwińska signed a €300 million loan to improve energy efficiency in some government-owned buildings.

Chernyshov also advocated for legally fixing gas prices for the population at the 2021 level and prohibiting penalties and fines during martial law.

Together with his team, he developed and implemented the "Shelter" social program, which provided compensation to households offering free temporary accommodation to IDPs.

In April 2022, Chernyshov was appointed by the government to oversee the urgent restoration of damaged residential, critical, and social infrastructure in liberated territories.

Together with the World Bank and the European Commission, Chernyshov prepared the Rapid Damage and Needs Assessment (RDNA) report—the first comprehensive evaluation of war consequences across 20 sectors.

Based on the report, Chernyshov's team created an emergency recovery program, prioritizing critical infrastructure objects for restoration by the end of 2022.

[12] Between May and June 2022, as part of this mission, Chernyshov and other representatives conducted 19 diplomatic visits to EU countries to support Ukraine's integration into the European Union.

[13] According to statements by German Chancellor Olaf Scholz, Chernyshov played a key role in influencing his perspective and providing a broader understanding of the situation in Ukraine.

[14] His priorities in office included corporate governance reform, strengthening Ukraine's energy independence by increasing gas production, and enhancing trust among international partners.

Under the leadership of Oleksiy Chernyshov, Naftogaz Group enterprises, JSC "Ukrgazvydobuvannya" and PJSC "Ukrnafta", produced over 13.2 billion cubic meters of gas in 2023.

[1] In 2014, Oleksiy Chernyshov founded the Kyiv Vision Foundation, an organization is dedicated to attracting investment to the country, supporting cultural projects and promoting Ukraine in Europe through the contemporary Ukrainian art.

In the fall of 2014, an exhibition of contemporary Ukrainian art "Through Maidan and Beyond" dedicated to Euromaidan events was successfully held in the Museumsquartier of Vienna (Austria).

Ukrainian art was presented by works of 23 artists, among them were Boris Mikhailov, Vlada Ralko, Sergey Bratkov, Nikita Kadan, Zhanna Kadyrova and others.

[21] In the same year Chernyshov supported the publication Awesome Kyiv, a modern guide to the Ukrainian capital that opened unknown places to people.