It runs from Store Kongensgade in the east to Rigensgade in the west, intersecting the streets Borgergade, Adelgade/Sankt Pauls Plads, Gammelvagt and Kronprinsessegade on the way.

Olfert Fischers Gade traces its history back to Christian IV's foundation of Nyboder naval barracks in 1931 but different sections of it were then known under individual names.

The section from Store Kongensgade was called Bryggerlængen (The Brewer Row), presumedly because a brewery was located at the site.

5 dates from the early 18th century,[3] Ut is built over eight bays in two storeys and has a three-bay gabled wall dormer.

[4] The central portion of the street, between Borgergade and Adelgade, is lined with Nyboder houses but do not date from Christian IV's original development but represent later models.

16-32 ), is an example of the so-called Grey Roys (or New Rows) that were built in the late 1880s and early 1890s to design by Olaf Schmidth and Rasmus Rue.