[3] Impressed, the following year she auditioned and was admitted into the Hochschule für Musik Hanns Eisler Berlin, where she studied under Brenda Mitchell.

[4] At the Hochschule, she had her first stage experience with Queen of the Night (The Magic Flute), and subsequently Zerbinetta (Ariadne auf Naxos), Belinda (Dido and Aeneas), Konstanze (Die Entführung aus dem Serail).

[5] During her studies, she sought university students who wanted to learn Russian and would offer German in return, to overcome her language barrier, and teamed up with a string quartet performing concerts at hospitals and retirement homes for extra living budget.

[9][6] From 2005 to 2007, she participated in the Young Artists' Program of the Hamburg State Opera, where she sang roles such as Papagena (The Magic Flute), Marie (Zar und Zimmermann), Oberto (Alcina), Barbarina (The Marriage of Figaro).

[10] She participated Alberto Zedda's Accademia Rossiniana in 2006, performing in Il viaggio a Reims (Contessa di Folleville) at the Rossini Opera Festival.

[18] Other performances included Adele in Die Fledermaus (Lyon),[19] Sofia in Il signor Bruschino (Graz), Fiakermilli in Arabella (Lübeck).

She received acclaim for her rendition of Mozart roles, including Blonde in Die Entführung aus dem Serail at the Liceu and Susanna in Florence.

[26] In 2012, she sang Adina in Baden-Baden and Lucia at the Deutsche Oper Berlin,[12] and performed in Carmina Burana under Paavo Järvi at the Rheingau Musik Festival.

[27] In 2013, she participated in a run of Lucio Silla conducted by Marc Minkowski as Giunia presented at the Mozartwoche, Salzburg Festival, and Musikfest Bremen.

[32] She was featured as Marfa in the premiere of Dmitri Tcherniakov's production of The Tsar's Bride at the Berlin State Opera, and later at La Scala.

[41] Peretyatko debuted to rave reviews as Violetta in La traviata at the Lausanne Opera in February 2015, followed by a new production of the same title at the Festspielhaus Baden-Baden.

[44] In 2016, she opened the Vienna Opera Ball together with Plácido Domingo,[45] and performed in Saint Petersburg: Mariinsky Theatre debut in La traviata,[46] and Classics at the Palace Square, concert celebrating the founding of the city.

[51][52] In summer, she returned to Berlin State Opera for her first Leïla in Bizet's Les pêcheurs de perles in Wim Wenders's take, conducted by Daniel Barenboim.

[58] On 29 June 2018 she announced on Facebook the filing of divorce and withdrawal from the upcoming production of Don Giovanni at the Teatro Comunale di Bologna which was conducted by her ex-husband.