[1] In 2018, Ayuso was cast in the Spanish Netflix television series Elite as Omar Shanaa, a closeted gay Muslim who develops a relationship with Ander Muñoz who is played by Arón Piper.

[7][8] Ayuso plays the character, David, in the upcoming film, 8 Años, a gay drama where he reflects on an eight-year relationship.

[9] Ayuso and Piper's onscreen relationship, coined "Omander", and offscreen friendship has generated a global following.

[5] Ayuso has had a transgressive image which includes provocative fashion choices in public appearances and social media posts.

[1] He is gay[5] and has stated that he is proud of his generation's social progress on topics including feminism, LGBT rights and efforts against racism.