[1][2] Omer Muhamed was born in Mogadishu, Somalia, where he lived until the age of six when his family moved to Cairo, Egypt.

[4] Mohamed signed with new United Soccer League club FC Cincinnati in January 2016.

[6] After spending time with USL League Two side Des Moines Menace,[7] Mohamed joined USL League One side Greenville Triumph SC on February 8, 2019, ahead of their inaugural season.

In September 2019, Mohamed was called into the Somalia national football team for its 2022 World Cup qualifiers against Zimbabwe.

[12] In December 2019 He was again called into the Somalia national football team for Its participation in 2019 CECAFA Cup held in Kampala, Uganda.