It is considered Velasquez's signature song and was released as the third single from her debut album Heavenly Place.

"On My Knees" is originally in the key of A Major, with a tempo of 93 beats per minute.

[3] Written in common time, Velasquez's vocal range spans from G#3 to E5 during the song.

Velasquez performed the song on the GMA Dove Awards.

[8] Ally Brooke covered the song in 2012 as her audition on the X Factor USA.