Once Upon a Time... Space (French: Il était une fois… l'Espace) is a science fiction animated television series created and directed by Albert Barillé.

The series was produced by French studio Procidis in co-production with France Régions (FR3, France), Société Radio-Canada (Canada), Radiotelevisione italiana (RAI, Italy), Katholieke Radio Omroep (KRO, Netherlands), Televisión Española (TVE, Spain), Crustel (Argentina), and Eiken (Japan) who was the one who made the animation.

In contrast to the show's success in the West, the series' Japanese broadcast was consigned to an early-morning time slot and attracted little attention, although it did gain a cult following in Japan in the following years.

The Japanese dub for the anime is considered to be a lost media due to it never having a home release and only re-aired on AT-X during the summer of 2006.

Among them there is the Omega Confederation (of which Earth is a member), the military Republic of Cassiopeia (led by General The Pest) and a powerful supercomputer which controls an army of robots.

Other episodes deal with the existence of God, the relationship of man with modernity and machines, the limits of technology, comparisons between armed peace under the rule of a dictator and the difficulty of maintaining order in a democracy, higher spiritual beings encountered at the beginning and the end of the series etc.