As the plague worsens, residents begin to experience amnesia, sending the town into chaos, but Melquíades returns from the dead with an antidote that quickly cures everyone.

[2] Prior to author Gabriel García Márquez's death in 2014, he had refused to sell the rights to the novel as he did not believe the time constraints of a film were sufficient for a proper adaptation.

[3][4] The series was filmed with the support of García Márquez's family, who requested that it be shot in Colombia, with Colombian actors, and in Spanish.

[5] The producers scouted several locations in Colombia, including Cali, Villavicencio, Girardot, Palomino, Santa Marta, and Barranquilla.

The website's consensus reads: "One Hundred Years of Solitude faithfully realizes Gabriel García Márquez's seminal novel with sumptuous polish, making for an adaptation that is nothing short of magical.

He commended the performances of the entire cast, specifically Soto, Cataño, and Marco Antonio González, and noted the care that seemed to have gone into the series' production.

[30] Judy Berman of Time wrote, "Considering the difficulty of the assignment, it's remarkable how close Netflix's splendid One Hundred Years of Solitude .

He commended García López and Mora's direction, calling the series "breathlessly beautiful at times, lyrical and alive and brimming with visual and intellectual ideas."

"[32] Aramide Tinubu of Variety called the series "exquisitely detailed and layered in intricate symbolism" and "one of the most faithful page-to-screen adaptations in recent years."

She commended the visuals of Paulo Pérez and María Sarasvati, the production design of Eugenio Caballero and Bárbara Enríquez [pt], and the ensemble's performance.

[34] Jack Seale of The Guardian rated the series three stars out of five, writing that it "might struggle with the novel's problematic sexual politics, but it's a big, gorgeous adaptation.

[35] Ed Potton of The Times rated the series two stars out of five, calling it "gorgeous but lethargic" and writing that it "lacks the vibrancy and energy of the novel".