The town is known locally for the "thousand cherry trees" which line the banks of the Natsui River.

Ono is located in north-central Fukushima prefecture in the middle of Abukuma Highland, in eastern Nakadōri.

Ono has a humid continental climate (Köppen Cfa) characterized by mild summers and cold winters with heavy snowfall.

[2] Per Japanese census data,[5] the population of Ono has declined steadily over the past 60 years.

The villages of Iitoyo, Natsui, and Ononiimachi were established with the formation of the modern municipalities system on April 1, 1889.