Due to the flat topography of Essex County, the land use surrounding Highway 77 is almost entirely agricultural.

Soil conditions in Essex are ideal for farming, and as a result very few natural areas can be found in the county.

[4] Several greenhouses are visible near the southern end of the highway, a small percentage of the over 815 hectares (2,000 acres) of land occupied by them in the Leamington area.

[5] The highway runs 11.5 km (7.1 mi) north through Mount Carmel and Blytheswood to the village of Staples before turning to the east.

[8] Highway 401 provides access to Windsor and the United States to the west, and to the town of Tilbury and city of Chatham–Kent to the east.

The busiest section of the highway lies at the southern end between Leamington and Blytheswood, with an average of 6,000 vehicles travelling it per day.

North of that, traffic drops considerably to 3,000 vehicles, but increases approaching Comber and Highway 401 to around 4,500.