Open Notebook Science Challenge

The challenge in turn forms part of the UsefulChem project, an ongoing open notebook science effort to synthesize and screen potential new anti-malarial drugs.

[2] The challenge began on September 28, 2008[3] and, as of February 2014, involves researchers and their students from at least 4 different institutions[4] and has resulted in the acquisition of over 7672 solubility measurements.

As well as concentrating on compounds related to the Ugi reaction, the ONSchallenge allows anyone to request a solubility measurement experiment.

[10] Sigma Aldrich is also an official sponsor of the Open Notebook Science Challenge.

Sigma Aldrich is participating by donating and shipping requested chemicals to any experimenters in the US or UK[11] for free.