Operation Destruct is a 1969 spy novel by Christopher Nicole written in the context of the Cold War and contests in international espionage between the West and the Soviet Union.

Agent Jonathan Anders promptly finds himself entangled in an international misadventure—with the Russians trying to exterminate him and the British police pursuing him for murder.

He becomes involved in a contest against the Russian agents, survives an attempt on his life, and becomes aware of a Soviet plot to poison a lot of people.

He discovers that Madam Cantelna, a Nobel Prize winning marine biologist, has a complete lab on board, and vials of some icky and revolting stuff that almost makes Helen vomit.

In his cross-country pursuit of Madam Cantelna, Jon travels beyond Scotland (after a preposterous stopover with a pop singer who supplies a jet) to the island rendezvous where Madam would meet another trawler and finish her research on population poisoning by fish pollution.