Oppah Chamu Zvipange Muchinguri-Kashiri (born 14 December 1958) is a Zimbabwean politician who serves as minister of defence in the cabinet of Zimbabwe since 2018.

Muchinguri ran as the ZANU-PF candidate for Mutasa Central constituency in the March 2008 parliamentary election, but was defeated by Trevor Saruwaka of the Movement for Democratic Change – Tsvangirai.

[3] The Herald reported on 3 January 2009, that Muchinguri had been dismissed from the Cabinet earlier in the week, along with 11 other ministers, because she no longer held any seat in Parliament.

[4] She was re-appointed to cabinet in 2014 following the dismissal of former Vice-President Joice Mujuru and several of her allies, in December 2014.

[8] In January 2021 Muchinguri was condemned by public health experts in Zimbabwe after accusing China of "botched experiments" that were responsible for the outbreak of the coronavirus pandemic in the world after Zimbabwe lost 2 cabinet ministers.