Opus de Blues is an album nominally led by saxophonist/flautist Frank Wess that was recorded in 1959 but not released on the Savoy label until it was first issued in Japan in 1984 and the United States in 1991.

Allmusic reviewer by Jim Todd stated, "Unlike some of the other Savoy releases in the Opus De series, this is not chamber jazz, but a relaxed, blowing session.

The five blues-based themes are pleasant, easygoing vehicles, familiar ground for any Basie associate.

The sound recording is good, accurately capturing the horns, rhythm section, and ensemble parts".

Track 9 is from the album Lee Morgan/Thad Jones Minor Strain (Roulette 94574), also recorded 1960.