She made one complete voyage as a slave ship in the triangular trade in enslaved people.

The Trans-Atlantic slave Trade Database describes her as having been launched in 1788, and to have been of United States registry.

1st voyage transporting enslaved people (1801–1802): Captain Thomas Payne sailed from Liverpool on 19 November 1801.

[4] 2nd voyage transporting enslaved people (1802): Captain Payne sailed from Liverpool on 11 February 1803.

[5] On 16 February, Orange Grove, Payne, master was driven ashore on the Half Mile Rocks.

Lloyd's List reported in April 1804 that the French had captured Orange Grove, Payne, master, as she was sailing to the West Indies from Africa.

[9] In May 1804 Lloyd's List reported that an Orange Grove, no master's name given, was at Jamaica, having come from Liverpool.