A common complaint regarding the building's design is that the narrowest staircase (capable of fitting only two people abreast) is in a central location; heavy between-period traffic often becomes congested in a bottleneck.

Students at Orchard Park High School can also participate in a strong theatrical program well known for their musicals and dramas.

On Saturday of that week there is a parade in the morning, the varsity football game in the afternoon, and the homecoming dance later that night.

In previous years, an annual Faculty Basketball Game was hosted to boost school spirit and to fund raise for charity.

Faculty members were drafted to play for one of four teams that correspond with grades 9–12, with the first selection given to the class that raised the most money that year.

In 2008, legendary football coach Gene Tundo made a dramatic 10 point half-court shot in the waning moments to propel the underdog Freshmen over the Seniors.

Various sports and clubs associated with the school also have their own social media accounts on X (formally Twitter), Instagram, and YouTube.

The Pulse is the school's annual magazine released every June, which features poetry, stories, pictures, and artwork from students.

The Quaker is the school's yearbook released every June, which features highlights of the year, including (but not limited to) students/faculty, clubs, events, and sports.