The Orchestre national des Pays de la Loire (ONPL) is a French symphony orchestra based in Angers and Nantes.

The orchestra receives support from the Regional Council of the Pays de la Loire, the French Ministry of Culture (Direction Régionale des Affaires Culturelles), the municipalities of Nantes and of Angers, and the General Councils of Loire-Atlantique, Maine-et-Loire, and La Vendée.

In 1971 these two orchestras united into a single organisation, the 114-member Orchestre Philharmonique des Pays de la Loire (OPPL), recruited by competition throughout France.

In April 2009, the ONPL announced the appointment of John Axelrod as its next music director, effective September 2010, with an initial contract of 3 years.

[3] Early recordings by the orchestra included orchestral works by Vincent d'Indy (Grand Prix du Disque, 1977), and music by Rabaud and Pierné (all EMI).