Orestes Destrade (born May 8, 1962) is a Cuban American former professional baseball infielder.

He played in Major League Baseball (MLB) for the New York Yankees, Pittsburgh Pirates, and Florida Marlins.

He graduated from Christopher Columbus High School in Miami, and later attended Florida College.

He played in 1988 with the Pittsburgh Pirates (where he was the victim of pitcher Randy Johnson's first major league strikeout), and 1993 and 1994 for the Florida Marlins.

Destrade also worked as an on-field reporter during the Tampa Bay Rays' 2010 postseason celebration after clinching a playoff spot.