The business school was established in 1959 and later named after Paul Orfalea, founder of Kinko’s.

In 1962, it became part of the Applied Arts Division, and in 1970, it was incorporated into the School of Business and Social Sciences.

The Orfalea College of Business is housed in a dedicated building that was opened in 1992.

The college’s facilities include classrooms, collaborative spaces, and specialized labs to support business education and innovation.

The college is situated in front of the Richard O’Neill Green lawn, providing a central location within the campus.The Cal Poly Center for Innovation and Entrepreneurship, established in 2010, is part of the Orfalea College of Business.