[1] O'Reilly played college basketball for Binghamton University from 2008 to 2012.
[2][3] After graduating from college, O'Reilly played for BK Lokomotiva Karlovy Vary of the Czech Women's Basketball League in the 2012–13 season.
[4] Her season ended early however due to a meniscus injury to her knee.
[4] In 2017, O'Reilly joined the Sunbury Jets of the Big V in Australia.
[4] For the 2018–19 season, O'Reilly joined KR of the Icelandic Úrvalsdeild kvenna, where she averaged 19.1 points and 8.9 rebounds per game.