Ortiz is a city in Venezuela's Guárico State, located in the country's central plains.

It serves as the administrative centre for the surrounding Ortiz Municipality.

The city was founded as a Roman Catholic mission in the late 16th century.

For a brief period between 1874 and 1881, Ortiz served as the state capital.

Ortiz is connected to Parapara to the North by a national road.