The Oscar Stanton De Priest House is a historic apartment building at 4536-4538 South Dr. Martin Luther King Jr. Drive in Chicago, Illinois,.

It is an architecturally-unexceptional three-story masonry structure built of brick with stone trim, with a full basement.

A native of Alabama, he migrated to Chicago in the late 19th century, where he gained employment as a building contractor.

In 1915, he was the first African-American to win a seat on Chicago's Board of Aldermen, representing the city's wealthy Second Ward.

As the first post-Reconstruction African-American in that body and the first from any northern state, De Priest became a prominent voice on matters of interest to African Americans, working in particular to secure equitable funding for the education of blacks.