[1] The school, formerly known as Asante Collegiate started as a private educational institution with just a handful of all boys’ students by the late Rev.

[1] After many years of private management, the school was taken over by the ministry of education in September, 1958; relocated it to Dichemso in September 1968; and renamed as Osei Kyeretwie (after Nana Sir Osei Ageyman Prempeh II, Otomfuo, the Asantehene) who was known in private life as Obarima Osei Kyeretwie.

In 1970, the current Tafo site of about 168-acre land was allocated to enable the school build permanent campus; the school has through 34 years operated from both the Dichemso and Tafo campuses.

[1] The philosophy or motto of the school is ‘’service to God and humanity”.

Products of the school are affectionately called ‘’AHENEMMA’’…princes and princesses.