Osiglia (Ligurian and Piedmontese: Oseria) is a comune (municipality) in the Province of Savona in the Italian region Liguria, located about 60 kilometres (37 mi) west of Genoa and about 25 kilometres (16 mi) west of Savona.

Osiglia borders the following municipalities: Bormida, Calizzano, Millesimo, Murialdo, Pallare, and Rialto.

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