Plodio (Ligurian: Ciòi; Piedmontese: Ploj) is a comune (municipality) in the Province of Savona in the Italian region Liguria, located about 50 kilometres (31 mi) west of Genoa and about 20 kilometres (12 mi) northwest of Savona.

It is in the Val Bormida near the Col di Cadibona.

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