[1] It is affiliated with the Faculty of Medicine of the University of Oslo and is one of the largest medical research institutions in Europe.

The hospital's academic tradition dates back to the establishment of the Faculty of Medicine of the Royal Frederick University in 1814, which itself was a continuation of the traditions of the University of Copenhagen and Rigshospitalet in Copenhagen following the 1814 Dano–Norwegian split.

[citation needed] Oslo University Hospital has 1,870 beds as of 2018, which is set to increase to 2,300 by 2028.

[4] Oslo University Hospital employs over 24,000 staff,[5] and is run as a public health trust.

[6] The hospital consists of fourteen medical divisions in addition to a central management unit, the director's office, and a division that provides non-medical services to the rest of the hospital.

The hospital is involved in extensive international and national network cooperation.