Osman Ghani Khan (1923-2000) was the former chairman of the United Nations Board of Auditors, a Bangladeshi civil servant, economist, Bangladesh Nationalist Party politician and a member of parliament for Pabna-2.

He joined the Bengal Civil Service as a Deputy Magistrate in 1946, initially serving at Barasat.

Khan transferred to the East Bengal Civil Service in 1947 and served as Additional District Magistrate of Dinajpur and Mymensingh.

From 1980 to 1982, Khan was elected as chairman of the United Nations Board of Auditors.

[2] After retirement, he was elected as a member of parliament from Pabna-2 as a Bangladesh Nationalist Party candidate in 1991.