After the death of captain Mehmed-beg Kulenović of Zvornik in 1806, Gradaščević received the title of Pasha for leading Bosnian forces against the First Serbian Uprising in 1812.

The famed Samson Cerfberr of Medelsheim is known to have served under his command north of Gradačac.

Osman Gradaščević died defending and aiding the captains of the Bosnian district of Zvornik against a Serbian incursion in 1812.

Known for his justice, he was killed by Dželaludin Paša, Vizier of Travnik due to his opposing of reforms.

Husein would go on to become one of the most famous figures in Bosnian history when he led the movement against the Ottoman military reforms of Sultan Mahmud II in 1831 and 1832.