Osmaston Manor was designed by Henry Isaac Stevens for Francis Wright of the Butterley Iron Company and completed in 1849.

Many aspects of the Manor's design mirrored Tissington Hall, the home of Wright's wife's family, the FitzHerberts.

Upon completion, Wright moved into the house with his family, and lived there until his death in 1873, when it was passed to his eldest son, John.

[3] Because of financial difficulties, the estate was sold in 1888 to Sir Andrew Walker's family, who had the house demolished when they moved to Okeover and adopted the Okeover name.

The house was used as a Red Cross hospital during World War II,[4] and demolished in 1964.