When he developed his interest in cartoons in 1943, he started working with Nino Pagot, who later created Calimero.
Cavandoli enjoyed worldwide recognition in 1969 with his character La Linea, a simply drawn cartoon born and lived out of a single white pencil stroke.
Cavandoli initially proposed his work for Carosello, an Italian advertisement break broadcast between 1957 and 1977.
Massimo Lagostina, the owner of a popular eponymous brand of cookware, chose it as a testimonial for his advertising campaign.
Following the success of the commercial, La Linea became the protagonist of an animated series subsequently adopted in many European countries.