In the song, Meek Mill illustrates how systemic racism has affected his life, through his own encounters with law enforcement.

[7] Backed by a "rumbling",[8] "thumping"[9] beat, the song, as noted by The Source's Miss2Bees, "amplifies the voices of ongoing protests against systemic racism and police brutality".

[7] "Otherside of America" opens with an audio dialogue of President Donald Trump's 2016 comments about the black community, in which he suggested they should vote for him because,[10] "You're living in poverty, your schools are no good, you have no jobs, 58 percent of your youth is unemployed – what the hell do you have to lose?".

Meek then juxtaposes Trump's statements, beginning his verse with: "Reporting live from the other side of America",[9] telling the story of when he "was just a shorty / then I started spittin' godly, and they said 'record me'", going back through his various times in jail while rising to fame.

In verified commentary with lyrics annotation website Genius, Meek explained the inspiration for its inclusion in the song: "This interview took place the morning Championships came out.

[13] ABC News Radio called the track "passionate", as Meek "expresses his anguish and fear towards police" following George Floyd's murder.