Otis is a town in Hancock County, Maine, United States.

There were 744 housing units at an average density of 30.0 per square mile (11.6/km2).

26.4% of all households were made up of individuals, and 8.6% had someone living alone who was 65 years of age or older.

There were 678 housing units at an average density of 27.2 per square mile (10.5/km2).

The racial makeup of the town was 98.90% White, 0.37% Native American, and 0.74% from two or more races.

25.8% of all households were made up of individuals, and 8.7% had someone living alone who was 65 years of age or older.