Otis Murphy (born 1972) is an American classical saxophonist and saxophone professor at Indiana University's Jacobs School of Music.

Murphy has primarily studied with esteemed saxophonists Eugene Rousseau and Jean-Yves Fourmeau.

He is an active saxophone soloist and clinician who is in great demand throughout the world.

In addition to his frequent solo appearances throughout the United States, he has also performed and given saxophone classes in France, Switzerland, Germany, the United Kingdom, Canada, Japan, Belgium, and Italy.

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