It was located 1.5 km south of downtown Ottawa in the Centretown neighbourhood and served buses from Greyhound Canada, Ontario Northland and Autobus Gatineau.

[1] It closed on June 1, 2021, and the land it sat on is now owned by Brigil, a real estate developer, who plans to build a multi-use space for housing, dining, retail, and other businesses.

Catherine Street lies directly north of Ontario Highway 417 (known locally as the Queensway), which is the main expressway through Ottawa.

On the north side of the station building, buses called at 14 outdoor bus stands with adjoining indoor gates.

[4] Historically, the majority of buses serving the station were operated by Voyageur Colonial Bus Lines (later Greyhound Canada.)

[15] In early 2010, Ottawa Mayor Larry O'Brien announced that he was working with Greyhound to move to bus terminal to a new location next to the Via Rail station on Tremblay Road,[16] effectively creating a transport hub along with the proposed LRT.

[17] According to O'Brien, talks had been going on for a while and Greyhound seemed warm to the idea, however the Catherine station's owner, Stewart Robertson, was never consulted and only learned through the media about the proposed move.

[18] The move sparked controversy and mixed opinions with the public and local politicians, stating that the proposed location is inconvenient as it is not central, or more convenient as it is along the Transitway.

[21] On March 11, 2011, it was revealed that Stewart Robertson had applied for rezoning of the lot to general mixed-use as a contingency plan if Greyhound were to leave.