Otto Christopher von Munthe af Morgenstierne (6 January 1735 – 17 March 1809) was a Danish civil servant, judge and landowner.

Ub 1657, Munthe af Gyldenstjerne was employed as a secretary in Danish Chancellery.

He became a member of the Generalitets- og Kommissariatskollegiet in 1783 but was dismissed in 1789, possibly due to his opposition to the abolition of the Stavnsbånd.

Otto Christopher von Munthe af Morgenstierne died at Hillerød on 17 March 1809.

A son by his second wife was judge (sorenskriver) in Bamble, Bredo Henrik von Munthe af Morgenstierne (1774–1835).