Pope Gregory XVI granted a canonical coronation to the image on 14 October 1838, via Cardinal Carlo Odescalchi, at the requested petition of the Roman seminarians.

The image was originally painted by Carlo Maratta, who gave it to a young noblewoman, Chiara Isabella Fornari, who later became Abbess of the Convent of the Poor Clares in Todi, Italy.

The patroness of Rome's Major Seminary is the Blessed Virgin Mary under the title Madonna della Fiducia.

Originally, this Madonna was located at the chapel of St. Louis at the Jesuit Collegio Romano, where was known as "Our Lady of Confidence".

I wish all of you the grace to find her guidance in your lives: from the image of Our Lady of Confidence to the goals that Providence foresees for you and even asks of you to be accomplished through you.