Ovandrotone albumin (INNTooltip International Nonproprietary Name, BANTooltip British Approved Name) (brand names Fecundin, Ovastim),[1] also known as polyandroalbumin, as well as ovandrotone:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine to increase the ovulation rate and number of lambs born to ewes.
[2][3][4][5] It is a conjugate of ovandrotone (androstenedione-7α-carboxyethylthioether)[6] and human serum albumin.
[7] This is thought to result in reduced negative feedback on the hypothalamic-pituitary-gonadal axis and increased gonadotropin secretion, which in turn improves fertility and fecundity.
[4] Indeed, ovandrotone albumin has been found to significantly increase luteinizing hormone levels throughout the estrous cycle in ewes.
This drug article relating to the genito-urinary system is a stub.