[2] They were first introduced in a story (in Super Friends #7-9) in which an alien villain called Grax (an old Superman foe) planted bombs on Earth's seven continents to destroy it.

Thanks to a warning from the Wonder Twins (in their first comic book appearance) the Justice League discovered the plan in time and recruited the heroes of the countries affected to find the bombs before they exploded.

However, it wasn't until DC Comics Presents #46 (June 1982) that they were introduced as a team,[3] in a story in which they helped Superman to stop an evil Atlantean sorcerer named Thaumar Dhai.

The Guardians eventually lost their UN funding to the Justice League, and the Dome was ordered to close, in part due to the political machinations of their enemy, Dr. Klaus Cornelius.

Some of its members left the team to join the League, notably Green Fury and Glacier, formerly known as Icemaiden (who changed their names to Fire and Ice).

In World War III, the Global Guardians assist the Marvel Family in an unsuccessful attack on Black Adam.

The Cadre is home to five Super Friends/Super Powers Collection doppelgangers: Black Vulcan (Mohammed Ibn Bornu), Apache Chief (Seneca), Samurai (Musashi), El Dorado (Xiuhtecutli), and Golden Pharaoh (Osiris).