Oxypetalum is a genus of flowering plants in the family Apocynaceae, first described with this name in 1810.

[3] The genus is native to South America.

[2][4][5][6][7][8] Oxypetalum coeruleum is cultivated as an ornamental.

As of November 2023[update], Plants of the World Online accepted the following species:[1] moved to other genera (Cynanchum, Morrenia, Philibertia, Tassadia, Tweedia)