He was elected and served as Member of the Legislative Assembly (MLA) five times for the Hyderabad constituency of Khairtabad until his death.

Reddy worked as a supervisor in the AP Electrical Equipment Corporation in Sanathnagar, Hyderabad.

He represented labour unions of Hyderabad Alwin, Kesavram Cements, NTPC and Vizag Steel factory.

[citation needed] Reddy suffered a heart attack on 28 December 2007, while on his way to a party meeting.

[5] P. Janardhan Reddy's statue was unveiled at the Khairatabad junction on the first anniversary of his death.

His daughter, Vijaya Reddy, started the PJR foundation in 2011 for the welfare of the common people.