PICMG currently focuses on developing and implementing specifications and guidelines for open standards–based computer architectures from a wide variety of interconnects.

The original PICMG mission was to provide extensions to the PCI standard developed by PCI-SIG for a range of applications.

The organization's collaborations eventually expanded to include a variety of interconnect technologies for industrial computing and telecommunications.

Since 2006, CP-TA had been a collaboration of communications vendors, developing interoperability testing requirements, methodologies, and procedures based on open specifications from PICMG, The Linux Foundation, and the Service Availability Forum.

In 2003, PICMG added an acronym-based naming convention for its specifications to yield better results from internet search engines.